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From Bioinformatics

Greetings and welcome to the Bioinformatics Research Group (MUBIG) at Macquarie University, Sydney.

The group was established by Prof. Shoba Ranganathan under the auspices of the Macquarie University Biotechnology Research Institute (MUBRI) and with support from the Division of Environmental and Life Sciences and the Department of Chemistry and Biomolecular Sciences, Macquarie University. We at MUBIG are a collegial and energitic group of researchers dedicated to make breakthrough discoveries in biological and biomedical sciences by applying genetic, genomic and computational approaches to address and solve the problems faced by the researchers in Molecular and Cellular Biology while also keeping our group interests and faculty research at the highest levels of excellence.

Areas of Interest and Research Focus

Our key areas of interest are biodiversity analysis, computational structural biology and comparative genome sequence analysis.

Computational structural biology Our research focuses on applying computational methods to help design vaccines of medicinal significance and therapeutic use for diseases like Bone marrow cancer. We are also keen to map disease causing mutations (especially in human) to the structure of the protein affected to predict the genotype-phenotype co-relation. Thus leading to drug and drug target designing and discovery.

Alternative Splicing events by whole genome comparisons Summary

Biodiversity Our research focuses on applying computational methods to help design vaccines of medicinal significance and therapeutic use for diseases like Bone marrow cancer. We are also keen to map disease causing mutations (especially in human) to the structure of the protein affected to predict the genotype-phenotype co-relation. Thus leading to drug and drug target designing and discovery.