Dr. Adrian Cootes

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Academic History



  • Senior Research Associate, Bioinformatics Laboratory, Macquarie University, 2008-
  • Research Associate, Structural Bioinformatics Group, Imperial College London, 2001-2007
  • Research Associate, Biomolecular Modelling Laboratory, Imperial Cancer Research Fund (now Cancer Research UK), 2000-2001
  • PhD (Chemistry), Australian National University, 2000
  • BSc 1st class honours (Medical Physics), University of New South Wales, 1996


Publications :



  • “The identification of similarities between biological networks: application to the metabolome and interactome”, AP Cootes, SH Muggleton and MJE Sternberg. J. Mol. Biol. 369: 1126-39 (2007)
  • “The automatic discovery of structural principles describing protein fold space”, AP Cootes, SH Muggleton and MJE Sternberg. J. Mol. Biol. 330: 839-850 (2003)
  • “Automatic determination of protein fold signatures from structural superpositions”, AP Cootes, SH Muggleton, RB Greaves and MJE Sternberg. Electronic Transactions on Artificial Intelligence. 5(B): 245-274 (2001)
  • “Automated protein design and sequence optimisation: Scoring functions and the search problem”, AP Cootes, PMG Curmi and AE Torda. Curr. Prot. Pept. Sci. 3: 255-271 (2000)
  • “Biased monte carlo optimisation of protein sequences”, AP Cootes, PMG Curmi and AE Torda. J. Chem. Phys. 113: 2849-2496 (2000)
  • “The dependence of amino acid pair correlations on structural environment”, AP Cootes, PMG Curmi, R Cunningham, C Donnelly and AE Torda. Proteins 32: 175-189 (1998)


Research interests



  • Systems biology
  • Network-based protein function prediction
  • Biological network comparison
  • Protein structure classification and analysis
  • Protein sequence optimisation


Contact Details



Room F7B 119

Chemistry and Biomolecular Sciences

Phone: 9850 8292


Email: acootes(at)cbms.mq.edu.au


Detailed CV

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